Analisis pengaruh program prolanis terhadap profil laboratorium pada pasien diabetes melitus tipe 2

Rindi Widiawati (Universitas Islam Sultan Agung)
Iskim Lutfha (Universitas Islam Sultan Agung)
Abrori Abrori (Universitas Islam Sultan Agung)
DOI: 10.56922/nmi.v3i5.1 Published: 2026-10-26 pp. 239-244
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Background: Type 2 diabetes mellitus (T2DM) requires continuous management to prevent complications. The Chronic Disease Management Program (Prolanis) is a promotive and preventive initiative aimed at improving patients’ quality of life.

Purpose: To analyze the effect of Prolanis on the laboratory profiles of patients with T2DM.

Method: This quasi-experimental study employed a one-group pretest–posttest design without a control group and was conducted at Tlogosari Kulon Primary Health Center, Semarang City. The sample consisted of 90 patients participating in Prolanis. Secondary data were obtained from medical records, including fasting blood glucose (FBG), HbA1c, urea, creatinine, high-density lipoprotein (HDL), low-density lipoprotein (LDL), and microalbumin levels. Data were analyzed using the Wilcoxon signed-rank test, with a significance level of 0.05.

Results: No statistically significant differences were found in any laboratory parameters before and after participation in Prolanis (p > 0.05), although some parameters showed a tendency toward improvement.

Conclusion: In this study, Prolanis did not demonstrate statistically significant changes in the laboratory profiles of patients with T2DM. Evaluation of program implementation and regular laboratory monitoring are necessary.

 

Keywords: Laboratory Profile; Prolanis; Type 2 Diabetes Mellitus.

 

Pendahuluan: Diabetes melitus (DM) tipe 2 memerlukan pengelolaan berkelanjutan untuk mencegah komplikasi. Program Pengelolaan Penyakit Kronis (Prolanis) merupakan upaya promotif dan preventif untuk meningkatkan kualitas hidup pasien.

Tujuan: Untuk menganalisis pengaruh Prolanis terhadap profil laboratorium pasien DM tipe 2.

Metode: Penelitian kuasi-eksperimental dengan rancangan one-group pretest–posttest tanpa kelompok kontrol dilakukan di Puskesmas Tlogosari Kulon, Kota Semarang. Sampel berjumlah 90 pasien peserta Prolanis. Data sekunder diperoleh dari rekam medis, meliputi gula darah puasa (GDP), HbA1c, ureum, kreatinin, HDL, LDL, dan mikroalbumin. Analisis dilakukan menggunakan uji Wilcoxon Signed-Rank dengan tingkat signifikansi 0.05

Hasil: Tidak ditemukan perbedaan yang bermakna secara statistik pada seluruh parameter laboratorium sebelum dan sesudah mengikuti Prolanis (p>0.05), meskipun terdapat kecenderungan perbaikan pada beberapa parameter.

Simpulan: Prolanis belum menunjukkan perubahan profil laboratorium yang bermakna secara statistik pada pasien DM tipe 2 dalam penelitian ini. Evaluasi pelaksanaan program dan pemantauan laboratorium secara berkala diperlukan.

 

Kata kunci: Diabetes Melitus Tipe 2; Profil Laboratorium; Prolanis.

Analisis pengaruh program prolanis terhadap profil laboratorium pada pasien diabetes melitus tipe 2. (2026). Journal of Nursing Management Issues, 3(5), 239-244. https://doi.org/10.56922/nmi.v3i5.1
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  1. Ahmed, A., Sattar, N., & Yaghootkar, H. (2022). Advancing a causal role of type 2 diabetes and its components in developing macro‐and microvascular complications via genetic studies. Diabetic Medicine, 39(12), e14982. https://doi.org/10.1111/dme.14982
  2. Aini, Z., Suardi, H. N., Dewi, F. M., Ibrahim, T., Waraztuty, I., & Mulia, V. D. (2025). Family Support and Medication Adherence in Patients in Prolanis Program. Majalah Kedokteran Bandung (MKB), 57(3), 203-211. hhttps://orcid.org/0000-0002-3112-0828
  3. Alkaff, F. F., Illavi, F., Salamah, S., Setiyawati, W., Ramadhani, R., Purwantini, E., & Tahapary, D. L. (2021). The impact of the Indonesian Chronic Disease Management Program (PROLANIS) on metabolic control and renal function of type 2 diabetes mellitus patients in primary care setting. Journal of Primary Care & Community Health, 12, 1–8. 10.1177/2150132720984409
  4. Badan Penyelenggara Jaminan Sosial Kesehatan. (2014). Panduan praktis PROLANIS (Program Pengelolaan Penyakit Kronis). https://unitkesehatan.ipb.ac.id/wp-content/uploads/2022/07/PANDUAN-PROLANIS.pdf?utm_source
  5. Dahlan, N. (2018, July). Pengaruh prolanis terhadap pengendalian gula darah terkontrol pada penderita DM di puskesmas Sudiang Kota Makassar. In Prosiding Seminar Nasional Sinergitas Multidisiplin Ilmu Pengetahuan dan Teknologi. https://www.scribd.com/document/461049982/Pengaruh-Prolanis-Terhadap-Pengendalian-Gula-Darah-Terkontrol-Pada-Penderita-Dm-Di-Puskesmas-Sudiang-Kota-Makassar
  6. Fatimah, R. N. (2015). Diabetes melitus tipe 2. Jurnal majority, 4(5), 93-101. https://www.academia.edu/104956223/Diabetes_Melitus_Tipe_2
  7. Faradiba, F., Anggriani, Y., & Maulidya, E. (2026). Hubungan antara Partisipasi dalam Program Prolanis dan Kadar Gula Darah Puasa pada Pasien Diabetes Tipe 2: Data dari Kota dengan Prevalensi Tinggi di Jakarta. PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia), 34-38. https://doi.org/10.30595/pharmacy.v23i1.29757
  8. Febriyanti, R. M., Irawan, A. A., Anggriani, N., Andriyana, Y., & Abdulah, R. (2025). Challenges in implementing Indonesia's community-based chronic disease management program (Prolanis): A scoping review. AIMS Public Health, 12(3), 890. 10.3934/publichealth.2025045
  9. Gustianto, V., Sadik, D., & Gusti, Y. T. (2020). Hubungan Dukungan Keluarga dalam Program Prolanis dengan Kepatuhan Minum Obat Pasien Diabetes Mellitus Tipe 2 di Puskesmas Rawat Inap Banjarsari Kota Metro Tahun 2019. Jurnal Ilmu Kesehatan Indonesia, 1(1), 1-11. https://doi.org/10.57084/jikmi.v1i1.301
  10. Gustika, E., Budiati, E., Rahayu, D., Adyas, A., & Putri, D. U. P. (2025). Factors Related to the Utilization of Chronic Disease Management Programs in Patients with Type 2 Diabetes Mellitus. Health Dynamics, 2(8), 359-365. https://doi.org/10.33846/hd20806
  11. Khasanah, A. N., Ananda, R. D. S., Nurinda, E., & Wulandari, A. S. (2026). Association Between Medication Adherence and Glycemic Control of Prolanis Participants With Type 2 Diabetes Mellitus Patients at Prambanan Public Health Center. Jurnal Farmasi Galenika, 13(2), 141-151. https://doi.org/10.70410/jfg.v13i2.427
  12. Manninda, R., Anggriani, Y., & Sari, A. K. (2021). Analisis dampak program pengelolaan penyakit kronis (Prolanis) dalam meningkatkan outcome klinis pasien diabetes melitus tipe 2 di Puskesmas Jakarta, Indonesia. Jurnal Ilmu Kefarmasian Indonesia, 19(2), 237-241. https://doi.org/10.35814/jifi.v19i2.1107
  13. Marwati, T. A., Kusmayanti, N. A., & Rosyidah, R. (2022). Quality of Life Among Diabetes Mellitus Patients in Indonesian Chronic Disease Management Program (Prolanis). Epidemiology and Society Health Review (ESHR), 4(2), 76-86. https://doi.org/10.26555/eshr.v4i2.5341
  14. Nuryana, M. I. R., Setiawan, H., & Pasaribu, M. M. (2024). Perbandingan Hasil Pemeriksaan Hba1c Antara Sebelum Dan Sesudah Mengikuti Prolanis Pada Pasien Diabetes Melitus Tipe 2 Di Laboratorium Kimia Farma Radio Dalam. Jurnal Fisioterapi dan Kesehatan Indonesia, 4(02), 226-234. https://physiohealthjournal.org/jfki/article/view/355
  15. Shofiyana, S., Jati, S. P., & Agushybana, F. (2026). Determinants of Prolanis Utilization in Diabetes Mellitus Patients as a Chronic Disease Management Program. Contagion: Scientific Periodical Journal of Public Health and Coastal Health, 8(1), 453-468. http://dx.doi.org/10.30829/contagion.v8i1.27218
  16. Sukohar, A., Rachman, R. E., Abighail, N., Lusina, S. E., & Ghani, M. A. (2026). Medication Adherence and Glycemic Control among Patients With Type 2 Diabetes Enrolled in a Chronic Disease Management Program in Primary Care Settings. International Journal of Health and Pharmaceutical (IJHP), 6(1), 450-458. https://doi.org/10.51601/ijhp.v6i1.571
  17. Suniyadewi, N. W., Sufyanti, Y., Kurniawati, N. D., Agustin, N. L. P. I. B., & Rismayanti, I. D. A. (2023). Quality of life on type 2 diabetes patients in Indonesia: Systematic review. JPMA. The Journal of the Pakistan Medical Association, 73(2), S140-S147. 10.47391/JPMA.Ind-S2-33
  18. Utami, A., Putri, L. P., & Hafidz, F. (2026). Clinical effectiveness of a chronic disease management program on glycemic control in type 2 diabetes mellitus: a difference-in-differences analysis in Indonesian primary care. Clinical Epidemiology and Global Health, 102430. doi.org/10.1016/j.cegh.2026.102430
  19. Wibowo, M. I. N. A., Yasin, N. M., Kristina, S. A., & Prabandari, Y. S. (2024). Systematic Review: Determinan Faktor yang Memengaruhi Kepatuhan Pengobatan Pasien Diabetes Tipe 2 di Indonesia. Media Penelitian dan Pengembangan Kesehatan, 31(4), 281-300.
  20. Widiarti, W., Salamah, S., Tan, F., Swannjo, J. B., Fa’iq, M. A. S., Rusli, A. A., ... & Alkaff, F. F. (2026). Health-related outcomes of chronic disease management program for diabetes mellitus in the Indonesian Eastern border region. Medical Journal of Indonesia, 35(2), 125-132. https://doi.org/10.13181/mji.oa.268179